very low density lipoprotein การใช้

• Apo-CIII is a component of very low density lipoprotein ( VLDL ).
• Release from the hepatocyte may involve the very low density lipoprotein secretory pathway.
• These cells release fatty acids directly into the liver, where they are converted into very low density lipoproteins.
• ApoB is essential in the assembly of very low density lipoproteins from lipids, in the liver and small intestine.
• A variant TM6SF2 gene causes susceptibility to nonalcoholic fatty liver disease due to impaired very low density lipoprotein ( VLDL ) production14.
• These lipases are closely related to each other and to lipoprotein lipase ( ), which hydrolyses triglycerides of chylomicrons and very low density lipoproteins ( VLDL ).
• In some human studies, the supplement increased blood levels of C-reactive protein, oxidized blood fats and very low density lipoprotein, along with reduced levels of high density lipoproteins.
• The elevated triglyceride levels ( > 5 mmol / l ) are generally due to an increase in very low density lipoprotein ( VLDL ), a class of lipoproteins prone to cause atherosclerosis.
• This condition is caused by a mutation in apolipoprotein E ( ApoE ), that serves as a ligand for the liver receptors for chylomicrons, IDL and VLDL or Very Low Density lipoprotein receptors.
• Bassen-Kornzweig disease, also called Bassen-Kornzweig Syndrome, is a rare congenital disorder in which the body fails to produce chylomicrons, a low density lipoprotein ( LDL ) and very low density lipoprotein ( VLDL ).
• In partnership with Abraham Kornzweig, Bassen identified Bassen-Kornzweig disease, a rare autosomal recessive disorder in which the body fails to produce chylomicrons, a low density lipoprotein ( LDL ) and very low density lipoprotein ( VLDL ).
• By targeted disruption experiments in mice, Trommsdorff et al . ( 1999 ) showed that 2 cell surface receptors, very low density lipoprotein receptor ( VLDLR; 192977 ) and apolipoprotein E receptor-2 ( ApoER2; 602600 ), are also required.
• Fulvestrant is slowly absorbed and maximum plasma concentrations ( Cmax ) are reached after about 5 days and the terminal half-life is around 50 days . Fulvestrant is highly ( 99 % ) bound to plasma proteins includiung very low density lipoprotein, low density lipoprotein, and high density lipoprotein.
• Berger " et al . ", in a study of the cholesterol-lowering properties of amaranth grain and oil in hamsters, report that amaranth oil significantly reduced non-HDL cholesterol and raised HDL cholesterol, as well as lowering very low density lipoprotein cholesterol ( VLDL cholesterol ) by 21 50 %.
• The liver converts unburned food metabolites into very low density lipoproteins ( VLDL ) and secretes them into plasma where they are converted to intermediate density lipoproteins ( IDL ), which thereafter are converted to low-density lipoprotein ( LDL ) particles and non-esterified fatty acids, which can affect other body cells.